Phylogeny of Na /Ca exchanger (NCX) genes from genomic data identifies new gene duplications and a new family member in fish species
نویسندگان
چکیده
Christian R. Marshall, Joanne A. Fox, Stefanie L. Butland, B. F. Francis Ouellette, Fiona S. L. Brinkman, and Glen F. Tibbits Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby; Cardiovascular Sciences, British Columbia Research Institute for Children’s and Women’s Health, Vancouver; Cardiac Membrane Research Laboratory, Simon Fraser University, Burnaby; and University of British Columbia, Bioinformatics Centre, University of British Columbia, Vancouver, British Columbia, Canada
منابع مشابه
Phylogeny of Na+/Ca2+ exchanger (NCX) genes from genomic data identifies new gene duplications and a new family member in fish species.
The Na+/Ca2+ exchanger (NCX) is a member of the cation/Ca2+ antiporter (CaCA) family and plays a key role in maintaining cellular Ca2+ homeostasis in a variety of cell types. NCX is present in a diverse group of organisms and exhibits high overall identity across species. To date, three separate genes, i.e., NCX1, NCX2, and NCX3, have been identified in mammals. However, phylogenetic analysis o...
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